Ambulatory Blood Pressure Monitoring in the Prediction of Cardiovascular Events and Effects of Chronotherapy

• Status: Completed
• Trial end date: 2009-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The MAPEC study was designed to investigate whether normalizing the circadian blood pressure profile towards a more dipper pattern (increasing the diurnal/nocturnal ratio of blood pressure) by the use of Chronotherapy (that is, taking into account the time of day of administration of antihypertensive medications) reduces cardiovascular risk.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Vigo
• Collaborators: Hospital Clinico Universitario de Santiago; Ministerio de Educacion y Ciencia, Spain; Xunta de Galicia
• Treatments: Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Carvedilol; Diuretics; Doxazosin; Enalapril; Indapamide; Lisinopril; Nebivolol; Olmesartan; Quinapril; Spirapril; Telmisartan; Torsemide; Valsartan

Criteria

Inclusion Criteria:

• Essential hypertension

Exclusion Criteria:

• AIDS

• shift workers

• secondary hypertension

• intolerant to ABPM