Amino Acid Chelated Iron Versus Ferrous Fumarate in the Treatment of Iron Deficiency Anemia With Pregnancy: Randomized Controlled Trial

• Status: Unknown status
• Trial end date: 2019-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

Anemia is the commonest hematological disorder that occurs in pregnancy. According to the recent standard laid down by 'WHO', anemia is present when the Hemoglobin (Hb) concentration in the peripheral blood is 11 gm/dl or less. The most common cause of anemia in pregnancy is lack of iron. This study is done to compare the efficacy and tolerability of iron amino acid chelate and that of iron salts (ferrous fumarat).

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ain Shams University
• Treatments: Ferrous fumarate; Iron; Iron Chelating Agents

Criteria

Inclusion Criteria:

• Pregnant women at 14 -18 weeks of gestation calculated from the first day of their last menstrual period and confirmed or modified by ultrasound

• Hemoglobin level 8-10.5 g/dL

• Serum ferritin<15µg/L

Exclusion Criteria:

• The presence of anemia from causes other than iron deficiency(e.g: Folat deficiency anemia,Vitamin B12 deficiency, ect…).

• Multiple gestations

• The presence of clinical and/or laboratory evidence of hepatic, renal, hematological or cardiovascular disease

• Patients with known gastritis

• History of mal-absorption syndrome

• Those with known hypersensitivity to iron preparations

• Those under current iron supplementation