Aminophylline on Perioperative Lung Mechanics in COPD Morbidly Obese Patients Undergoing Laparoscopic Bariatric Surgery

• Status: Recruiting
• Trial end date: 2024-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to evaluate the usefulness of adding aminophylline to dexmedetomidine intravenous infusion intraoperatively on oxygenation and lung mechanics in chronic obstructive pulmonary disease (COPD) morbidly obese patients undergoing bariatric surgery.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Tanta University
• Treatments: Aminophylline; Dexmedetomidine

Criteria

Inclusion Criteria:

• Age from 20 to 60 years.

• Patients scheduled for laparoscopic bariatric surgery not exceeding three hours under general anesthesia.

• American Society of Anesthesiologists (ASA) class II to III.

• Patients who had no previous abdominal surgery.

• Patients with a body mass index (BMI) greater than 40 kg/m2and suffered obstructive lung disease diagnosed by pulmonary function tests (; forced vital capacity (FEV1\FVC) < 70%).

• Patients who are psychologically normal.

Exclusion Criteria:

• Patients who refuse to participate.

• Those with arrhythmia or receiving anti-arrhythmic medications.

• Those with significant coexisting diseases (e.g. kidney, heart, liver).

• Those with known allergy to any of allocated drugs.

• Those with excessive intraoperative blood loss more than allowable amount to every patient.