Amlodipine Plus Botulinum Toxin for Focal Dystonia
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Objective: To determine if the calcium channel blockers, amlodipine can augment the effect of
botulinum toxin injections in the treatment of focal dystonia.
Study Population: 20 patients with cervical dystonia
Design: Double-bind, placebo-controlled clinical trail.
Outcome measures: For patients: dystonia rating scales (Twistrs, Fahn-Marsden dystonia scale,
NINDS subjective patient rating scale), and hand grip strength. For healthy volunteers:
Amplitude of EDB MEP.
Phase:
Phase 2
Details
Lead Sponsor:
National Institute of Neurological Disorders and Stroke (NINDS)