Amniotic Membrane Therapy for Interstitial Cystitis/Painful Bladder Syndrome

• Status: Not yet recruiting
• Trial end date: 2026-06-01
• Target enrollment: 0
• Participant gender: Female

Summary

Interstitial cystitis/painful bladder syndrome (IC/PBS) is a clinical syndrome in which patients report symptoms of bladder and/or pelvic pain with pressure and/ or discomfort associated with urinary frequency and urgency.

The primary objective of this study is to determine the efficacy of amniotic membrane therapy in patients with interstitial cystitis/painful bladder syndrome (IC/PBS) as defined by clinically-significant improvement in validated symptom questionnaires.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: David Sheyn

Criteria

Inclusion Criteria:

• Patients 18 years of age or older

• Female

• English Speaking

• Diagnosis of IC/PBS

• Have failed at least one prior treatment for IC/PBS

Exclusion Criteria:

• Patients less than 18 years of age

• Unable to provide consent

• Non-English speaking

• Patients with known anatomical malformations of the ureters, bladder, or urethra