Ampicillin / Sulbactam vs. Ampicillin / Gentamicin for Treatment of Chorioamnionitis
Status:
Completed
Trial end date:
2012-06-01
Target enrollment:
Participant gender:
Summary
Chorioamnionitis is an infection of the placenta and amniotic membranes (bag of waters)
surrounding the baby inside of a pregnant woman prior to delivery. This infection is somewhat
common and is routinely treated with antibiotics given to the mother both before and after
the baby is born. Currently it is not known what is the best choice of antibiotics to treat
this type of infection, but commonly used treatments include Unasyn (ampicillin/sulbactam) or
ampicillin/gentamicin. We plan to compare these two different antibiotic regimens to see if
one is better than the other at treating and preventing bad outcomes from chorioamnionitis in
women and babies.