An Efficacy and Safety of Proprietary Formulations of Oral Ketamine + Aspirin in Treatment of Acute
Status:
Recruiting
Trial end date:
2021-12-31
Target enrollment:
Participant gender:
Summary
Headaches affect over 50% of patients annually, with close to 4% of ED visits for headache.
Most headaches managed in the ED are benign, with 90% of these headaches classified as
tension, migraine, or cluster. At present, the satisfaction with ED treatment of headache is
low, and despite the multitude of available medications, the evidence- based treatment
options are often quite limited. There are over twenty different types of medications
available to the ED clinicians for managing headache, many with different routes of
administration (parenteral, intranasal, subcutaneous, and oral). Many of these medications
are provided in so-called "headache cocktail", which varies based on the physician,
institution, and patient preferences.