An Evaluation of Dupilumab in Patients With Nasal Polyposis And Chronic Symptoms Of Sinusitis
Status:
Completed
Trial end date:
2014-11-01
Target enrollment:
Participant gender:
Summary
Primary Objective:
To evaluate the efficacy of dupilumab (SAR231893/REGN668) in the treatment of bilateral Nasal
Polyposis (NP) by assessment of the endoscopic nasal polyp score (NPS) in comparison to
placebo.
Secondary Objectives:
To evaluate effect of dupilumab with regards to:
- symptoms of sinusitis,
- sinus computed tomography (CT) scan,
- NPS in the sub-group of participants with co-morbid asthma,
- Safety and tolerability.