An Evaluation of the Efficacy and Safety of Tegaserod 6 mg Bid Given Orally to Chinese Patients With Chronic Constipation
Status:
Completed
Trial end date:
2005-10-01
Target enrollment:
Participant gender:
Summary
Tegaserod is an aminoguanidine indole compound and a member of a new class of
5-hydroxytryptamine (5-HT) agonists. Activation of 5-HT4 receptors triggers the release of
neurotransmitters from the enteric nerves which in turn stimulate contractility and
peristalsis. This study will investigate the efficacy and safety of tegaserod against chronic
constipation in a Chinese population of adult men and women