An In Vivo Model for Postinflammatory Hyperpigmentation
Status:
Unknown status
Trial end date:
2017-12-01
Target enrollment:
Participant gender:
Summary
Post-inflammatory hyperpigmentation (PIH) is an acquired hypermelanosis that occurs after
cutaneous inflammation or injury that frequently affects darker skinned populations.
Previously, a model of 35% TCA-induced PIH was validated against acne induced PIH, which has
value in product testing for the treatment of PIH. In this second phase of the study, the
investigators would like to determine if a lower concentration of TCA-induced PIH is
comparable to acne-induced PIH.