An Interaction Study of Ketoconazole/Verapamil Versus AZD1305

• Status: Completed
• Trial end date: 2008-11-01
• Target enrollment: 0
• Participant gender: Male

Summary

The purpose is to study whether ketoconazole or verapamil have an effect on how AZD1305 is handled by the body, i.e the absorption, distribution, metabolism and excretion, when administered in combination with AZD1305.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: AstraZeneca
• Treatments: Ketoconazole; Verapamil

Criteria

Inclusion Criteria:

• A body mass index (BMI=weight/height2) of 19 to 30 kg/m2

Exclusion Criteria:

• Potassium outside normal reference values

• ECG findings outside normal range