Overview

An Investigational Study of Hydrocortisone

Status:
Completed
Trial end date:
2014-11-01
Target enrollment:
Participant gender:
Summary
This study will investigate a new drug called InfacortĀ®; a newly-developed immediate release formulation of a well-established drug called hydrocortisone. Hydrocortisone is used as a replacement treatment for people whose adrenal glands are not producing enough natural cortisol - a condition known as adrenal insufficiency. The study will assess how InfacortĀ® acts once inside the body, by measuring cortisol and other hormone levels in the body, compared to already marketed hydrocortisone tablet and hydrocortisone intravenous (through the vein) injection. The population who are eligible to take part in the study are healthy male volunteers, aged between 18 and 60 years of age.
Phase:
Phase 1
Details
Lead Sponsor:
Diurnal Limited
Collaborator:
Simbec Research
Treatments:
BB 1101
Cortisol succinate
Dexamethasone
Dexamethasone 21-phosphate
Dexamethasone acetate
Hydrocortisone
Hydrocortisone 17-butyrate 21-propionate
Hydrocortisone acetate
Hydrocortisone hemisuccinate