Overview

An Open-Label Study to Evaluate the Safety and Efficacy of Ublituximab in Combination With TGR-1202 for Patients Previously Enrolled in Protocol UTX-TGR-304

Status:
Enrolling by invitation
Trial end date:
2025-03-01
Target enrollment:
0
Participant gender:
All
Summary
This is a multi-center, open-label, study to evaluate the safety and efficacy of ublituximab (TG-1101) in combination with TGR-1202 for patients who have progressed on treatment arms previously enrolled in Protocol UTX-TGR-304
Phase:
Phase 2
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
TG Therapeutics, Inc.
Criteria
Inclusion Criteria:

- Prior treatment in clinical trial UTX-TGR-304

- Eastern Cooperative Oncology Group (ECOG) score of 0 to 2

Exclusion Criteria:

- Patients refractory to ublituximab + TGR-1202

- Transformation of CLL to aggressive Non-Hodgkin's Lymphoma (NHL) (Richter's
transformation)