An Open-Labeled Pilot Study of Biomarker Response Following Short-Term Exposure to Metformin
Status:
Terminated
Trial end date:
2014-08-01
Target enrollment:
Participant gender:
Summary
The goal of this clinical research study is to learn more about the possible effects of
metformin extended release (ER) in patients with colon cancer or adenomas who are about to
have surgery. The safety of this drug will also be studied.
Metformin-ER is commonly used to control blood sugar levels in patients with diabetes. It is
also designed to block a protein in tumor cells that is important in tumor growth and blood
vessel development. This may cause cell death or reduce the spread of the disease.