An Open, Single Centre, Randomised, Parallel Group Study to Investigate Three Different Immunosuppressive Regimens
Status:
Completed
Trial end date:
2010-06-01
Target enrollment:
Participant gender:
Summary
An open, single center, randomised study to investigate three different immunosuppressive
regimens for de novo renal transplant recipients:
1. st sirolimus / EC-MPS / tacrolimus regimen
- After 3 months a protocol biopsy is performed. If no rejection is detected the
calcineurin inhibitor (tacrolimus) is withdrawn.
2. nd everolimus / EC-MPS / tacrolimus regimen
- After 3 months a protocol biopsy is performed. If no rejection is detected the
calcineurin inhibitor (tacrolimus) is withdrawn.
3. rd tacrolimus / EC-MPS / prednisone regimen - After 3 months a protocol biopsy is
performed. If no rejection is detected prednisone is withdrawn.