An RCT of Oseltamivir in Outpatients With CPD: A Pilot Study.

• Status: Withdrawn
• Trial end date: 2015-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The proposed pilot study will provide needed data to establish the feasibility of a conducting a large randomized controlled trial as to the effectiveness of the use of oseltamivir early in the course of influenza in outpatients with chronic pulmonary disease.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: McMaster University
• Treatments: Calcium Carbonate; Oseltamivir

Criteria

Inclusion Criteria:

• Clinic patients with physician diagnosed chronic obstructive pulmonary disease

• respirologist-diagnosed non-cystic fibrosis bronchiectasis and pulmonary fibrosis (based on appropriate clinical, exposure, and radiological criteria as per American Thoracic Society guidelines)

• Participants will be drawn from the respirology clinics and will be randomized if within 72 hours of meeting criteria for influenza-like illness

Exclusion Criteria:

• residents of nursing homes

• patients who are immunosuppressed

• patients on immunosuppressive does (15 mg or more) of prednisone for three weeks or longer