Anabolic Steroids and Exercise in Hemodialysis Patients

• Status: Completed
• Trial end date: 2004-10-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a study to find out whether an exercise program during dialysis or a drug called nandrolone decanoate can increase muscle size and strenght in patients on dialysis.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Treatments: Nandrolone; Nandrolone Decanoate; Nandrolone phenpropionate

Criteria

Inclusion Criteria:

• end-stage renal disease on hemodialysis for 3 or more months

Exclusion Criteria:

• inadequate dialysis; Kt/V <1.2

• nonadherent to dialysis treatments; missing >2 dialysis sessions in the month prior to screening

• catabolic state; HIV with opportunistic infection in the last 3 months, malignancy, or infection requiring intravenous antibiotics within 2 months prior to screening

• unable to give informed consent

• active intravenous drug use

• contraindications to resistance exercise; myocardial infarction within 6 months, active angina, uncompensated congestive heart failure, orthopedic or musculoskeletal limitations