Anabolic Steroids for Nutritional Rehabilitation of Critically Ill Patients

• Status: Terminated
• Trial end date: 2007-10-01
• Target enrollment: 0
• Participant gender: All

Summary

This prospective, double-blinded study will determine the feasibility of determining the efficacy of a weekly intramuscular injection of nandrolone (an anabolic steroid) in malnourished ICU patients.The data from this study will also enable us to prepare a future grant proposal with a calculated sample size necessary to demonstrate an improvement in clinical outcome.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Lawson Health Research Institute
• Treatments: Nandrolone; Nandrolone Decanoate; Nandrolone phenpropionate; Testosterone Congeners

Criteria

Inclusion Criteria:

1. anticipated length of stay in ICU >10 days

2. moderate to severe malnutrition

3. patient tolerating enteral feeds

Exclusion Criteria:

1. age < 18 yrs

2. known allergy to nandrolone

3. women of child bearing age with positive pregnancy test

4. contraindications to intramuscular injections ie anticoagulation

5. renal failure requiring renal replacement therapy

6. patients with breast or prostate cancer -