Aim of this double-blind, randomized, controlled clinical trial is to compare the safety and
the efficacy of anakinra over placebo for the management of patients with hidradenitis
suppurativa (HS) of Hurley II and Hurley III disease stage. Patients will be evaluated on
subsequent follow-up visits. Two scores will be applied: disease activity as assessed in the
protocol by the investigator; and Sartorius score. Primary efficacy endpoint will be the
comparisons of visual analogue scores, of disease activity, of Sartorius score and of
dermatology life quality index between the two groups of treatment over follow-up.