Analgesia After Total Knee Replacement Surgery

• Status: Completed
• Trial end date: 2014-04-01
• Target enrollment: 0
• Participant gender: All

Summary

Postoperative pain after total knee replacement surgery is difficult to treat. Mobilisation and hospital discharge might be delayed. Recent research shows that intra-articular infiltration with local anesthetics and perioperative prescription of gabapentin can improve outcome.

Objective of the study: Comparison of mobilisation speed and postoperative NRS-scores of patients after total knee replacement surgery which is treated with epidural analgesia or peroperative infiltration of the knee. Appraisal of the value of gabapentin for reduction of postoperative opiate consumption.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: St. Antonius Hospital
• Treatments: Bupivacaine; Gabapentin; gamma-Aminobutyric Acid; Ropivacaine; Sufentanil

Criteria

Inclusion Criteria:

• 18 years or older and legally responsible

• Waiting for total knee replacement surgery

• Informed consent

Exclusion Criteria:

• Contraindications for epidural analgesia

• Aortic Valve stenosis

• Severely compromised cardiac function

• infection near epidural punction site

• Redo knee surgery

• Previous arthrotomies

• Allergy/Hypersensitivity for study mediation or all other used medication

• Participation in other studies