Analgesia Effects of Intravenous Ketamine After Spinal Anesthesia for Non-elective Cesarean Section

• Status: Completed
• Trial end date: 2019-03-07
• Target enrollment: 0
• Participant gender: Female

Summary

This randomized double blind study will be conducted in pregnant woman planned for non elective cesarean section under spinal anesthesia. Ketamine group will receive intravenous 0.25 mg/kg and placebo group will receive same amount of normal saline after spinal anesthesia prior to skin incision. Postoperative outcomes measures are total opioid consumption and pain scores for 24 hrs.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: B.P. Koirala Institute of Health Sciences
• Treatments: Analgesics; Ketamine

Criteria

Inclusion Criteria:

• • All women at term(>or =37 weeks of gestation)

• Healthy

• American Society of Anesthesiologists(ASA) class1 and 2

• Women undergoing non-elective caesarean section whose anesthetic plan is for spinal anesthesia with bupivacaine and fentanyl

Exclusion Criteria:

• • Women with American society of anesthesiologist physical status>2

• Body mass index >or =40 kg per square meter

• Height <150 cm

• Any contraindication to the spinal anesthesia

• History of substance abuse

• History of hallucinations

• Chronic opioid therapy

• Chronic pain or on any pain medication currently

• Patient with maternal complications,like cardiovascular disease pre-eclampsia,diabetes,multiple gestation,known fetal abnormality

• Cases with severely compromised fetus where immediate administration of general anesthesia is required.