Analgesia Effects of Nalbuphine vs Sulfentanil

• Status: Unknown status
• Trial end date: 2018-01-01
• Target enrollment: 0
• Participant gender: Female

Summary

Cesarean section may result in great trauma and postoperative pain. Besides incision pain, uterine contraction pain is another source of postoperative pain after cesarean section. In clinical practice, a large amount of uterine contraction agent is routinely applied after cesarean section so as to promote involution of uterus and reduce postoperative hemorrhage, which also causes great uterine contraction pain. Acute pain is the risk factor of chronic pain, and may postpone the recovery from labour and influence the quality of life of parturient. Though various analgesia modules have been attempted, more than 20% parturients still experience severe postoperative pain, and pain management after cesarean section remains a challenge to anesthesiologists.

This study aim to compare the effects of nalbuphine hydrochloride vs sufentanil citrate on patient-controlled intravenous analgesia after cesarean section.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Fudan University
• Treatments: Dsuvia; Flurbiprofen; Flurbiprofen axetil; Nalbuphine; Ramosetron; Sufentanil

Criteria

Inclusion Criteria:

• For primipara with selective cesarean section

Exclusion Criteria:

• Severe preeclampsia,

• pregnancy complicated with diabetes mellitus

• pregnancy complicated with cardiac disease,

• gestation age<37W

• recently use of opiate drugs or nonsteroidal antiinflammatory drugs within 48 h before operation