Analgesic Benefit of Preoperative vs. Postoperative Etoricoxib in Total Knee Arthroplasty

• Status: Completed
• Trial end date: 2014-09-01
• Target enrollment: 0
• Participant gender: All

Summary

Evaluation of the efficacy of preemptive versus postoperative administration of etoricoxib in total knee arthroplasty (TKA).

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Foisor Orthopedics Clinical Hospital
• Treatments: Analgesics; Etoricoxib

Criteria

Inclusion Criteria:

• ASA I-III

• weight (kilos) over 40 kg

• height (centimeters) over 155 cm

• non-anemic

• indication for primary TKA (total knee arthroplasty)

Exclusion Criteria:

• history of asthma

• peptic ulcer

• severe hepatic or renal dysfunction

• neuropathies

• bleeding disorders

• uncooperative

• drug abuse

• sensibility to etoricoxib

• paracetamol or morphine

• long acting nonsteroidal antiinflammatory drugs (NSAID) in the last 4 days preoperative

• cerebrovascular and peripheric vascular disease

• arterial hypertension (HTA) not adequately controlled

• congestive heart failure.