Analgesic Effect of Anahil and Ibuprofen on Pain After Root Canal Therapy in Patients With Pulpitis of the Molars in Qazvin(a City in Iran)

• Status: Not yet recruiting
• Trial end date: 2022-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Hypothesis:

0: The analgesic effect of Ibuprofen and Anahil would be the same in reducing the pain after root canal therapy.

1: Ibuprofen shows higher potency to reduce the pain after root canal therapy.

1: Anahil shows higher potency to reduce the pain after root canal therapy.

1. combination of the Anahil and Ibuprofen would have more effective results in reducing the pain post endodontic treatment.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Qazvin University Of Medical Sciences
• Treatments: Ibuprofen

Criteria

Inclusion Criteria:

1. Patients report spontaneous pain of the first molar of mandible ranging from 50 to 100 mm on a VAS (0-100 mm)

2. The dental pulp's condition is irreversible pulpitis and the tooth is reparable and need the root canal therapy

3. No evidences of any lesions and lucency, PDL widening, loss of lamina dura in radiographic examination

4. Patients aged 20 to 50 years from both genders

5. Patients are not pregnant or breast-feeding

6. Healthy periodontal status (no evidences of aggressive/chronic periodontal diseases)

7. No history of any systemic diseases (specially gastrointestinal and coagulation disorders)

8. No history of allergic reaction to food nutrients (specially pineapple, celery, carrot, and fennel), NSAIDs and lidocaine

9. No history of consuming the drugs interfere with NSAIDs, lidocaine and anticoagulants

10. No use of other analgesic drugs within the last 6 hours

11. Existence of no large restorations or crowns in treated tooth

12. patients have no extreme fear of dental procedure

13. Teeth with no evidence of infection or sinus tract

14. Patients did not a previous RCT

Exclusion Criteria:

1. Patients who leave the study because of any reasons

2. Special anatomy of teeth (extra canals, severe root curvature, calcifications, open apex, C shape, fractures,..)

3. Patients who are not able to tolerate the single-session treatment (time, tooth's situation,..)

4. If the aspiration through IAN block injection is positive

5. If the diagnosis of pulp status has changed to partial necrosis during access cavity preparation