Overview

Analgesic Effect of Ketamine Vs Ketamine Magnesium Infusion and Their Effect on Postoperative Morphine Consumption

Status:
Completed
Trial end date:
2022-05-15
Target enrollment:
0
Participant gender:
All
Summary
Ketamine and magnesium-ketamine are two analgesics that are being studied for use as adjuvants. They were shown to have anaesthetic and analgesic properties, and as a consequence of this finding, it has been postulated that they may have a role in minimising the requirement for analgesic drugs during the postoperative period. The major objective of the research was to examine the pain-relieving effects of ketamine vs ketamine magnesium infusion, as well as their influence on postoperative morphine consumption following nephrectomy; the secondary goal is to assess hemodynamic effects and pain severity.
Phase:
Phase 1
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Egymedicalpedia
Treatments:
Ketamine
Morphine
Criteria
Inclusion Criteria:

- Patients with elective nephrectomy

Exclusion Criteria:

- Pregnant women

- Cases with severe chronic disease as liver cell failures, CHF

- cases with allergies to ketamine and magnesium sulphate

- cases with a history of current regular use of (analgesic, anticonvulsant,
antidepressant)

- chronic pain.

- mental illness.