Analgesic Effects of Gabapentin After Scoliosis Surgery in Children

• Status: Completed
• Trial end date: 2010-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The primary aim of this study is to determine whether the use of gabapentin will improve postoperative analgesia and reduce opioid consumption and side effects in children undergoing corrective spinal surgery for idiopathic scoliosis. Secondary aims are to evaluate whether use of gabapentin reduces pain scores, decreases postoperative nausea and vomiting, decreases persisting pain and improves patient satisfaction.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The Hospital for Sick Children
• Treatments: Analgesics; Gabapentin; gamma-Aminobutyric Acid

Criteria

Inclusion Criteria:

• 10 - 17 years of age

• scheduled for elective surgical correction of scoliosis

• able to operate a patient-controlled analgesia (PCA) pump

Exclusion Criteria:

• unable to cooperate

• unable to operate the PCA pump

• unable to rate pain

• have a known allergy or sensitivity to gabapentin or morphine

• have a history of chronic pain or daily analgesic use

• have taken acetaminophen, a non-steroidal anti-inflammatory drug, or an antacid within a 24-hour period prior to surgery