Overview

Analgesic Efficacy of Duloxetine in Patients Undergoing Lumbar Discectomy

Status:
Unknown status

Trial end date:
2019-12-25

Target enrollment:
0

Participant gender:
All

Summary

Duloxetine is a serotonin-norepinephrine reuptake inhibitor primarily used for treatment of major depression and anxiety. Duloxetine also has been used in the treatment of chronic pain conditions, such as osteoarthritis and musculoskeletal pain. There are few studies examining its effect for acute pain. The objective of this study is to evaluate the analgesic effect of duloxetine for patients undergoing lumbar discectomy.

Phase:

N/A

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Assiut University

Treatments:

Analgesics
Anesthetics
Atracurium
Atropine
Cisatracurium
Duloxetine Hydrochloride
Fentanyl
Isoflurane
Neostigmine
Propofol

Criteria

Inclusion Criteria:

- Patients undergoing lumbar discectomy

Exclusion Criteria:

- Patients on regular opioid therapy

- Uncontrolled hypertensive patients

- Patients with ischemic heart disease