Analgesic Efficacy of Ropivacaine Alone or in Combination With Adjuvants on Post-operative Analgesia Following Video-Assisted Thoracoscopic Surgery.

• Status: Recruiting
• Trial end date: 2022-08-31
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the study is to investigate the analgesic effects of the subcutaneous wound infiltration with tramadol, ketamine, dexamethasone, dexmedetomidine and midazolam as adjuvant to ropivacaine, compared to ropivacaine alone in patients undergoing Video-Assisted thoracoscopic Surgery (VATS) procedures.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Aga Khan University
• Treatments: Analgesics; BB 1101; Dexamethasone; Dexamethasone acetate; Dexmedetomidine; Ketamine; Midazolam; Ropivacaine; Tramadol

Criteria

Inclusion Criteria:

1. ASA I to III.

2. Age >18 years.

3. Either sex.

4. Elective Video assisted thoracotomy surgery (VATS) under general anaesthesia

Exclusion Criteria:

1. ASA IV & V.

2. Coagulation disorders.

3. Infection at the vicinity of the surgical wound.

4. Raised intracranial pressure.

5. History of hypersensitivity or known allergy to any study drug.

6. History of opioid addiction.

7. History of seizure disorder.

8. Those who are not willing to participate in the study.

9. Allergy to local anesthetics.

10. Duration of surgery greater than 2 hours.