Analgesic Preoperative/Postoperative Dexketoprofen Trometamol in Third Molar Surgery

• Status: Completed
• Trial end date: 2015-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the present investigation is to evaluate the effectiveness of the preoperative administration of Dexketoprofen Trometamol, employing the third molar surgery model, when compared to postoperative administration of the same drug. It was hypothesized that preoperative oral Dexketoprofen trometamol will reduce the intensity of pain by 30% after 8 hours of the surgery, when compared with post-operative administration.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Daniel Chavarría Bolaños
• Treatments: Analgesics; Dexketoprofen trometamol; Ketoprofen

Criteria

Inclusion Criteria:

• Healthy volunteers between 18-28 years old

• Clinical and radiographic diagnosis of impacted mandibular third molars, which the surgical approach may include flap and osteotomy procedures.

• surgery classified as simple to moderate

• Voluntary acceptance of written consent, previously approved by institutional ethics committee

Exclusion Criteria:

• Prior administration of analgesic or anti-inflammatory drugs

• History of drug dependence

• History of allergic reactions to any of the drugs selected, or local anesthetics

• Simultaneous presence of oral pathologies that may interfere with the surgical procedure