Analgo-Sedative Effects Of Oral, Or Nebulized Ketamine In Pre-schoolers Undergoing Elective Surgery.

• Status: Completed
• Trial end date: 2019-06-01
• Target enrollment: 0
• Participant gender: All

Summary

the primary objective of this study is to investigate the sedative, and analgesic effects of oral, or nebulized ketamine as premedication drugs, and providing postoperative analgesia for the preschoolers and decrease their need for systemic analgesia.The secondary objective is to compare each sedation technique after oral, or nebulized ketamine for safety ,and procedural outcomes.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Zagazig University
• Treatments: Analgesics; Hypnotics and Sedatives; Ketamine

Criteria

Inclusion Criteria:

• Parents acceptance.

• Age (3-6) years old.

• American Society of Anesthesiologist physical status (ASA) I / II

• Elective surgery of approximately half to one hour duration under general anesthesia.

• Child With Body Mass Index (BMI) (15-18kg/m²)

Exclusion Criteria:

• Parents refusal.

• Altered mental status, and epilepsy.

• History of allergy to ketamine.

• Recent respiratory tract infection.

• Sever dysfunction of the central nervous system.

• Increased intracranial pressure, and increased intra-ocular pressure.

• Cardiac dysrhythmia ,and/or congenital heart disease.