Clinical Retina research studies often collect aqueous samples in hopes of estimating levels
of drug or cytokines in the vitreous. Little is known about how well vitreous and aqueous
correlate. This study will collect vitreous and aqueous samples at the same time to evaluate
and compare drug and cytokine levels.
The overall objective of this study is to evaluate the molecular concentration of growth
factors, cytokines and chemokines in human aqueous humor and vitreous samples collected from
individuals undergoing pars plana vitrectomy for tractional retinal detachment secondary to
proliferative diabetic retinopathy, exudative or tractional retinal detachment secondary to
macular degeneration, macular hole or neovascular glaucoma.