Analysis of Atropine and Propranolol Induced Changes

• Status: Completed
• Trial end date: 2012-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to learn the effects of genetic make up on response to the drugs atropine and propranolol, to examine how changes in heart rate and blood pressure can be measured, and to test a new statistical analysis method.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: National Institute on Aging (NIA)
• Treatments: Atropine; Propranolol

Criteria

Inclusion Criteria:

• Healthy male and female volunteers

• Ages 21-40

• Body Mass Index >18.0 and <27.0

Exclusion Criteria:

• History of any chronic illnesses including cardiac diseases and bleeding problems

• Drug use of any kind

• Participation in any clinical trial within the last month

• Tobacco use and/or alcohol abuse

• Use of dietary supplements and unwillingness to refrain