Multicenter, double-blind, randomized, placebo-controlled study to evaluate the efficacy and
safety of anamorelin HCl. Approximately 100 subjects with advanced PDAC and cachexia will be
randomized 1:1 to anamorelin HCl 100 mg or placebo, taken orally once daily (QD) for a total
of 25 weeks. Subjects will be instructed to take the study drug at least 1 hour before their
first meal of the day