Anecortave Acetate Injection to Treat Steroid-responsive Intraocular Pressure Increase in Cornea Transplant Patients
Status:
Terminated
Trial end date:
2010-09-01
Target enrollment:
Participant gender:
Summary
This study will investigate the use of anecortave acetate injection to reduce intraocular
pressure (IOP) in corneal transplant recipients who are experiencing steroid-associated
pressure control problems. Alternative methods of IOP control have been shown to entail
serious risks. For example, reduction of topical steroids increases the risk of graft
rejection, and use of glaucoma medications or glaucoma surgery increases the risk of graft
failure. This study is designed to have sufficient power to detect whether a single injection
can induce a clinically significant IOP reduction.