Anesthetic Agents and Acute Kidney Injury After Liver Resection Surgery
Status:
Unknown status
Trial end date:
2016-12-01
Target enrollment:
Participant gender:
Summary
- It has been shown that patients who undergo liver resection surgery are at high risk for
postoperative acute kidney injury (AKI).
- Sevoflurane may increase the risk for postoperative AKI because of production of
compound-A.
- Therefore, we have planned to investigate the effects of different anesthetic agents on
postoperative renal function.
- Patients undergoing liver resection surgery are randomized into 2 groups.
- One of the groups receives sevoflurane and the other group receives desflurane.
- Blood and urine specimen are sampled both pre- and postoperatively, and several
biomarkers are compared between the groups.