Anesthetic Depth Effects Upon Immune Competent Cells
Status:
Completed
Trial end date:
2013-03-01
Target enrollment:
Participant gender:
Summary
Anesthesia depth affects the proliferation of lymphocytes to NK-cells and memory T-cells
effect and the phagocytosis activity of macrophages in healthy patients. ASA 1-3 subjects
undergoing extended shoulder surgery under continuous regional anesthesia randomly were
assigned to a deep or a shallow anesthesia level (BIS <35 or >55) for more than an hour.
Immune response is measured by lymphocyte proliferation as well as neutrophil and monocyte
phagocytosis activity.