Angiotensin Converting Enzyme (ACE) Inhibition and Peripheral Arterial Disease
Status:
Completed
Trial end date:
2012-01-01
Target enrollment:
Participant gender:
Summary
Leg pain caused by peripheral arterial disease (PAD) can severely impede walking ability. Our
preliminary findings indicate that the drug ramipril is much more effective in improving
walking ability than current therapies. To be accepted as a new treatment for PAD these
findings require validation in a much larger clinical trial.We propose to examine the effects
of ramipril therapy for 6 months in a randomized, controlled trial of patients with PAD. If
positive, this study will identify ramipril as a potential new therapy for PAD.