Antagonism Research Between Antiemetics Agents and Acetaminophen in Thyroidectomy's Post-operative Analgesia.

• Status: Completed
• Trial end date: 2011-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of our study is to determine if there is an antagonism between drugs used in the prevention of postoperative nausea and vomiting (PONV) on the analgesia led by acetaminophen after thyroidectomy.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Lille
• Treatments: Acetaminophen; Antiemetics; BB 1101; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Droperidol; Ondansetron

Criteria

Inclusion Criteria:

• patients undergoing thyroidectomy without lymph node dissection

• American Society of Anesthesiologists physical status from I to III

• Apfel-score equal to 2

• informed consent signed

Exclusion Criteria:

• pregnant and breast-feeding women

• addictive disorders

• psychic diseases

• allergy or contra-indication to a drug used in the study

• presence of postoperative nausea or vomiting

• administration of glucocorticoid for protecting recurrent laryngeal nerve.

• protocol not respected

• protocol refused by the patient

• intellectual handicap