Antenatal Corticoid Therapy for Late Preterm Babies

• Status: Completed
• Trial end date: 2010-05-01
• Target enrollment: 0
• Participant gender: Female

Summary

This study aims to determine the effectiveness of antenatal corticosteroid therapy in late preterm babies. The investigators hypothesis is corticoid accelerates fetal lung maturation even after 34 weeks and reduces risk of respiratory distress syndrome and other neonatal morbidities.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Instituto Materno Infantil Prof. Fernando Figueira
• Treatments: Betamethasone; Betamethasone acetate phosphate; Betamethasone benzoate; Betamethasone sodium phosphate; Betamethasone Valerate; Betamethasone-17,21-dipropionate

Criteria

Inclusion Criteria:

• Pregnancy between 34 and 36 weeks

• Confirmed gestational age (LMP, USG)

• Alive fetus

• Imminent risk of preterm delivery

Exclusion Criteria:

• Multiple pregnancy

• Major fetal malformations

• Comproved fetal lung maturity

• Maternal or fetal indication for immediate interruption of pregnancy

• Maternal hemorrhagic syndromes (placenta previa, abruptio placenta)

• Chorioamnionitis

• Chronic use of corticosteroids

• Previous use of corticosteroids for fetal lung maturation in the current pregnancy