Overview Anti-PD 1 Brain Collaboration + Radiotherapy Extension (ABC-X Study) Status: Recruiting Trial end date: 2025-08-01 Target enrollment: Participant gender: Summary This is a phase II, open label, randomised trial of ipilimumab and nivolumab with concurrent intracranial stereotactic radiotherapy versus ipilimumab and nivolumab alone in patients with asymptomatic, untreated melanoma brain metastases. Phase: Phase 2 Details Lead Sponsor: Melanoma Institute AustraliaCollaborator: Bristol-Myers SquibbTreatments: Antibodies, MonoclonalIpilimumabNivolumab