Overview

Anti-angiogenesis Combine With EGFR-TKI in Advanced Non-squamous Non Small Cell Lung Cancer

Status:
Unknown status
Trial end date:
2020-02-20
Target enrollment:
Participant gender:
Summary
Epidermal growth factor receptor Tyrosine kinase inhibitor (EGFR TKI) have been approved to treat NSCLC harboring EGFR mutation as first-line therapy. However, the acquired resistance of EGFR-TKI is a common and severe problem.The study explore the superiority of anti-angiogenesis drugs (Apatinib, endostatin, anlotinib) plus EGFR TKI versus single EGFR-TKI.
Phase:
Phase 2
Details
Lead Sponsor:
Xinqiao Hospital of Chongqing
Treatments:
Angiogenesis Inhibitors
Erlotinib Hydrochloride
Gefitinib