Overview

Anti-inflammatories and Adolescent Schizophrenia

Status:
Unknown status
Trial end date:
2020-12-01
Target enrollment:
0
Participant gender:
All
Summary
A double-blind controlled trial assessing the efficacy of anti-inflammatories on symptoms and cognition of adolescents with schizophrenia
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Hospital Psiquiatrico Infantil Dr. Juan N. Navarro, Mexico
Treatments:
Anti-Inflammatory Agents
Celecoxib
Minocycline
Criteria
Inclusion Criteria:

- Diagnosis of schizophrenia or schizophreniform disorder.

- Patients in their first psychotic episode or previously diagnosed

- No specific pharmacological treatment (antipsychotic at therapeutic doses in regular
doses) in the previous two weeks.

- Have a responsible parent or guardian.

Exclusion Criteria:

- Active infection

- Chronic somatic diseases, including autoimmune diseases

- Comorbidity with anorexia, substance use disorders

- Pregnancy

- Use of anti-inflammatory medications or antibiotics