Anti-inflammatory Effect of Atorvastatin on Graft Donor Kidney

• Status: Completed
• Trial end date: 2014-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Renal Insufficiency is a priority disease in health system, which may require renal replacement therapy based on renal transplantation, which is considered as therapy of choice. During the procedure of renal transplantation, the graft could be damaged by ischemia-reperfusion which generates complications in its function.

Recently the anti-inflammatory and immunomodulatory effects of statins have been emphasized, which could be beneficial in renal transplantation.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Instituto Mexicano del Seguro Social
• Treatments: Anti-Inflammatory Agents; Atorvastatin; Atorvastatin Calcium

Criteria

Inclusion Criteria:

• Accepted as kidney donor

• Voluntary participation

• Informed consent accepted

• 85% fulfillment of atorvastatin treatment

Exclusion Criteria:

• Hypersensibility to Atorvastatin

• Smoking