Antibacterial Effect of Light-activated Calcium Silicate Versus Light-activated Calcium Hydroxide

• Status: Unknown status
• Trial end date: 2019-09-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a randomized clinical study. 48 subjects with a confirmed diagnosis of deep carious molars without pulpal lesions were randomized to one of two treatments: Patients treated with Light-cured calcium silicate (Theracal) liner, or treated with light-cured calcium Hydroxide (Biner LC) liner. Both two Treatments are with the step-wise excavation Technique.

Treatment will be done at baseline, collecting dentin sample before application of liner material, then patients will be dismissed with Resin-modified Glass Ionomer restoration and recalled after 6 months. Re-entry of tooth required for completing the step-wise excavation technique collecting the second dentin sample after this time interval (6 months) and permanently restore tooth with composite restoration. Dentin samples will be microbiologically analyzed and the results will be statistically calculated.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Cairo University
• Treatments: Anti-Bacterial Agents; Calcium; Calcium, Dietary

Criteria

Inclusion Criteria:

1. Normal adults will be recruited in this study, all the volunteers participated in this experiment will be healthy looking with free medical history.

2. Subjects aged between 18-40 years.

3. In each patient required one or two deep carious tooth occlusally either upper or lower permanent molars.

4. All volunteers must be with good oral hygiene in order to restore with composite restorations.

5. Subjects were required to be available for the duration of the study, and to sign an informed consent form

Exclusion Criteria:

1. Subjects with a history of allergy to any of the drugs or chemicals used in the study.

2. Subjects with carious anterior tooth are not within the study.

3. History of pulp pathology of the teeth which indicates root canal treatment is not included in the study.

4. Pregnancy and Lactating mothers.

5. Patients with any systematic problems or mental or physical disability.