Antibacterial-coated Sutures at Time of Cesarean

• Status: Recruiting
• Trial end date: 2022-01-01
• Target enrollment: 0
• Participant gender: Female

Summary

Abdominal closure with antibacterial-coated sutures has been shown to reduce wound infections after a number of surgical procedures, but none of the previous trials included cesarean delivery. Our objective is to determine whether use of antibacterial-coated sutures reduces surgical site infection (SSI) after cesarean delivery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The University of Texas Medical Branch, Galveston
• Treatments: Anti-Bacterial Agents; Triclosan

Criteria

Inclusion Criteria:

• 18-50 years of age.

• Women ≥ 24 weeks' viable gestation.

• To undergo cesarean delivery.

Exclusion Criteria:

• Patient unwilling or unable to provide consent.

• No prenatal care or a non-resident patient who is unlikely to be followed-up after delivery.

• Immunosuppressed patients: i.e., taking systemic immunosuppressant or steroids (e.g. transplant patients; not including steroids for lung maturity), HIV with CD4<200, or other.

• Decision to use other than suture closure (e.g. secondary wound closure, mesh closure).

• Skin infection.

• Coagulopathy.

• High likelihood of additional surgical procedure beyond cesarean (e.g. scheduled hysterectomy, bowel or adnexal surgery).

• Allergy to Triclosan.

• Incarcerated individuals.