Antibiotic/COPD in Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) Requiring Mechanical Ventilation
Status:
Completed
Trial end date:
2005-06-01
Target enrollment:
Participant gender:
Summary
Although the use of antibiotics in the treatment of acute exacerbation of chronic obstructive
pulmonary disease (COPD) is largely accepted, controversy remains regarding whether the
choice of antibiotic has any impact on outcome. Our aim was to compare the effects of the
combination of trimethoprim and sulfamethoxazole and ciprofloxacin in patients treated for
severe COPD exacerbation requiring mechanical ventilation.
Phase:
Phase 3
Details
Lead Sponsor:
University of Monastir
Treatments:
Ciprofloxacin Fluoroquinolones Sulfamethoxazole Trimethoprim Trimethoprim, Sulfamethoxazole Drug Combination