Antibiotic Prophlaxis for High-risk Laboring Women in Low Income Countries
Status:
Completed
Trial end date:
2020-10-01
Target enrollment:
Participant gender:
Summary
This study, performed over a course of 3 years in 5 collaborating hospitals in Cameroon,
Africa, will randomize 750 women in labor with prolonged rupture of membranes ≥ 8 hours or
prolonged labor ≥ 18 hours to identical oral regimens of 1 gram of azithromycin, 1 gram of
azithromycin+2 grams of amoxicillin or placebo. Women will be followed to ascertain maternal
infectious outcomes and perinatal outcomes.