Antibiotic Prophylaxis for Early Ventilator-associated Pneumonia in Neurological Patients
Status:
Withdrawn
Trial end date:
2011-03-01
Target enrollment:
Participant gender:
Summary
This study seeks to assess whether coma patients really benefit from the use of antibiotics
as a prophylactic for reducing the incidence of early ventilator-associated pneumonia in this
population group. For this we consider the use of ampicillin sulbactam antibiotic which has a
low ability to induce resistance, efficacy and safety observed during the time that has been
used, even in patients with neurosurgical pathology, and to be broadly available in our
environment.
Our hypothesis is that neurological patients in coma state, requiring mechanical ventilation,
the application of antibiotic prophylaxis compared with placebo reduces the incidence of
early ventilator-associated pneumonia.