Antibiotic Prophylaxis for Transrectal Prostate Biopsy-Ciprofloxacin vs. Trimethoprim/Sulfamethoxazole

• Status: Unknown status
• Trial end date: 2020-05-01
• Target enrollment: 0
• Participant gender: Male

Summary

This study will examine if a single dose of Ciprofloxacin and Trimethoprim/Sulfamethoxazole are equivalent for prophylaxis immediately prior to prostate biopsy, when a patient has a suspected prostate cancer.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Umeå University
• Treatments: Anti-Bacterial Agents; Antibiotics, Antitubercular; Ciprofloxacin; Sulfamethoxazole; Trimethoprim

Criteria

Inclusion Criteria:

• Indication for trans rectal prostate biopsy (Physicians discretion)

• Informed consent

Exclusion Criteria:

• Diabetes Mellitus

• Indwelling urinary catheter

• Prior urinary infection (last 6 months)

• Dipstick positive (Nitrites test)

• Allergy to Ciprofloxacin or Trimethoprim/Sulfamethoxazole

• Severe liver disease

• Concomittant use of Tizanidine

• Immunosuppression