Antibiotic Therapy in Erupted Tooth Extractions

• Status: Completed
• Trial end date: 2019-01-30
• Target enrollment: 0
• Participant gender: All

Summary

Evaluation of the efficacy of amox+clav and of a probiotic after tooth extraction. the aim is to evaluate efficacy of antibiotic therapy after tooth extractions in preventing infections as compared to no therapy, and efficacy of probiotics in preventing gastro-intestinal adverse effects during the antibiotic treatment. The number of patients to be included is 150. The study products are: Amoxicillin + Clavulanic Acid and Bifidobacterium Longum and Lactoferrin.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Antonio Barone
• Treatments: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Antibiotics, Antitubercular; Clavulanic Acid; Clavulanic Acids; Lactoferrin; Sulfalene

Criteria

Inclusion Criteria:

• Patients who needed tooth extractions

• Patients older than 18 years

• Patients able to understand and to sign a consent form

Exclusion Criteria:

• General contraindications to oral surgery

• Third molar or impacted tooth extractions

• Patients treated or under treatment with immunosuppressive agents or patients immunocompromised

• Patients treated or under therapy with amino-bisphosphonate and anti-angiogenetic intravenous medications

• Patients who received head and neck irradiation treatments

• Patients who were diagnosed with uncontrolled diabetes

• Patients suffering from renal failure

• Pregnancy and breastfeeding patients

• Patients diagnosed with drug and alcohol addiction

• Patients who suffer from psychiatric disorders

• Patients diagnosed with allergy to penicillin and probiotic